The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10653770 B1

PDF
Full Text
Expired
Date of Patent:
May. 19, 2020

Filed:

Sep. 23, 2019
Applicants:

Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);

Children's Medical Center Corporation, Boston, MA (US);

Inventors:

Stephen C. Harrison, Brighton, MA (US);

Bing Chen, Chestnut Hill, MA (US);

Dan Barouch, Boston, MA (US);

Joseph P. Nkolola, Watertown, MA (US);

Michael Scott Seaman, West Roxbury, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/21 (2006.01); C07K 14/005 (2006.01); A61K 39/12 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/21 (2013.01); A61K 39/12 (2013.01); C07K 14/005 (2013.01); C12N 7/00 (2013.01); A61K 2039/53 (2013.01); A61K 2039/54 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55566 (2013.01); A61K 2039/575 (2013.01); C12N 2740/16051 (2013.01); C12N 2740/16122 (2013.01); C12N 2740/16134 (2013.01); C12N 2740/16171 (2013.01);
Abstract

Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided.


Find Patent Forward Citations

Harrison, Stephen. (2020). Biochemically stabilized hiv-1 env trimer vaccine (U.S. Patent No. 10653770). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10653770

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