The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2020
Filed:
Mar. 12, 2015
Applicant:
Bavarian Nordic A/s, Kvistgaard, DK;
Inventors:
Assignee:
Bavarian Nordic A/S, Kvistgaard, DK;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/21 (2006.01); A61K 39/02 (2006.01); A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 39/12 (2006.01); A61K 39/285 (2006.01); A61K 39/155 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); A61K 39/155 (2013.01); A61K 39/285 (2013.01); A61K 2039/5254 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/55566 (2013.01); A61K 2039/57 (2013.01); C12N 2710/24121 (2013.01); C12N 2710/24134 (2013.01); C12N 2710/24143 (2013.01); C12N 2760/18534 (2013.01); C12N 2770/24134 (2013.01); Y02A 50/388 (2018.01);
Abstract
The invention relates to compositions, uses, and methods for inducing an immune response against a vaccinia virus. The addition of an oil and water emulsion to MVA can vastly increase the B cell response and particularly neutralizing antibodies against vaccinia virus and encoded recombinant antigens. Thus, the addition of an oil and water emulsion to MVA can increase the protective immune response. The invention encompasses administering a dose of an MVA in an oil and water emulsion to an animal, especially a human.