The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2020
Filed:
Jul. 07, 2016
Applicant:
University of Florida Research Foundation, Incorporated, Gainesville, FL (US);
Inventor:
Alexandra Rose Lucas, Gainesville, FL (US);
Assignee:
University of Florida Research Foundation, Incorporated, Gainesville, FL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61P 37/06 (2006.01); A61K 39/275 (2006.01); A61P 37/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/001 (2013.01); A61K 39/275 (2013.01); A61P 37/06 (2018.01); A61K 2039/58 (2013.01); C12N 2710/24033 (2013.01);
Abstract
Disclosed here are polypeptides, derived from the Myxomavirus-derived secreted glycoprotein, M-T7, comprising point mutations that interfere with chemokine-glycosaminoglycan binding. Compositions containing such M-T7 derived polypeptides with point mutations are therefore useful in preventing, blocking and/or reducing rejection of a transplant.