The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2020
Filed:
Feb. 23, 2018
Applicant:
Fred Hutchinson Cancer Research Center, Seattle, WA (US);
Inventors:
Cameron J. Turtle, Seattle, WA (US);
Stanley R. Riddell, Sammamish, WA (US);
Assignee:
Fred Hutchinson Cancer Research Center, Seattle, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0783 (2010.01); A61K 39/00 (2006.01); G01N 33/50 (2006.01); A61K 35/17 (2015.01);
U.S. Cl.
CPC ...
A61K 39/00 (2013.01); A61K 35/17 (2013.01); C12N 5/0636 (2013.01); C12N 5/0638 (2013.01); G01N 33/505 (2013.01); A61K 2039/515 (2013.01); A61K 2039/57 (2013.01); A61K 2039/572 (2013.01); C12N 2501/599 (2013.01); G01N 2333/54 (2013.01); G01N 2333/70557 (2013.01);
Abstract
This invention provides, among other things, methods for the identification and isolation of viable putative long-lived antigen-specific memory CD8T cell subsets (CMhi and EMhi) with high surface expression of CD161 and/or IL-18Rα and the capacity to rapidly efflux the fluorescent dye Rh123.