The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2020
Filed:
Aug. 25, 2016
Janssen Pharmaceutica NV, Beerse, BE;
Tongfei Wu, Jette, BE;
Dirk Brehmer, Geel, BE;
Lijs Beke, Antwerp, BE;
An Boeckx, Herentals, BE;
Gaston Stanislas Marcella Diels, Turnhout, BE;
Ronaldus Arnodus Hendrika Joseph Gilissen, Kasterlee, BE;
Edward Charles Lawson, Pipersville, PA (US);
Vineet Pande, Vosselaar, BE;
Marcus Cornelis Bernardus Catharina Paradé, Eindhoven, NL;
Wim Bert Griet Schepens, Sint Katelijne Waver, BE;
Johannes Wilhelmus John F. Thuring, Antwerp, BE;
Marcel Viellevoye, Breda, NL;
Weimei Sun, Lower Gwynedd, PA (US);
Lieven Meerpoel, Beerse, BE;
Janssen Pharmaceutica NV, Beerse, BE;
Abstract
Embodiments of the present invention relate to 6-6 bicyclic aromatic ring substituted nucleoside analogues, including, for example, the following compound: Embodiments of the present invention also relate to uses of the disclosed compounds for the inhibition of protein arginine methyltransferase 5 (PRMT5).