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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10653667 B1

PDFFull Text
Date of Patent:
May. 19, 2020

Filed:

Sep. 25, 2014

Drug for preventing, treating or preventing metastasis of giant cell tumor that occurs in bone or soft parts, chondrosarcoma, or osteosarcoma, local injection for arterial embolization, and artificial bone

Applicant:

Nippon Chemiphar Co., Ltd, Tokyo, JP;

Inventors:

Akihiko Takeuchi, Ishikawa, JP;

Hiroyuki Tsuchiya, Ishikawa, JP;

Assignee:

NIPPON CHEMIPHAR CO., LTD, Tokyo, JP;

Attorney:

Greenblum & Bernstein, P.L.C.

Primary Examiner:

Karen A Canella

Int. Cl.
CPC ...
A61K 31/38 (2006.01); A61K 39/395 (2006.01); A61K 31/427 (2006.01); C07K 16/28 (2006.01); A61K 31/425 (2006.01); A61K 45/06 (2006.01); A61L 31/14 (2006.01); A61L 27/54 (2006.01); A61L 31/04 (2006.01); A61L 31/16 (2006.01); A61K 31/4439 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61K 31/38 (2013.01); A61K 31/425 (2013.01); A61K 31/427 (2013.01); A61K 31/4439 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); A61L 27/54 (2013.01); A61L 31/045 (2013.01); A61L 31/048 (2013.01); A61L 31/145 (2013.01); A61L 31/146 (2013.01); A61L 31/148 (2013.01); A61L 31/16 (2013.01); C07K 16/2875 (2013.01); G01N 33/5011 (2013.01); A61L 2430/36 (2013.01); C07K 2317/21 (2013.01); C07K 2317/76 (2013.01);
Abstract

The present invention provides an agent for prophylactic treatment, therapeutic treatment, or prevention of metastasis of giant cell tumor occurring in a bone and soft tissue, chondrosarcoma, or bone sarcoma, a local infusion for artery embolization, and an artificial bone, which comprises a substance having a PPARγ-agonistic activity and/or a PPARγ expression-inducing activity as an active ingredient. The agent for prophylactic treatment, therapeutic treatment, or prevention of metastasis, the local infusion for artery embolization, and the artificial bone of the present invention are a radical therapeutic agent or radical therapeutic material that can cause apoptosis in giant cell tumor occurring in a bone and soft tissue, chondrosarcoma, or bone sarcoma to make the tumor disappear, and can induce differentiation of the tumor into fat cells to make the tumor disappear.

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