The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2020
Filed:
Oct. 06, 2014
Applicants:
Io Therapeutics, Inc., Santa Ana, CA (US);
Trustees of Dartmouth College, Hanover, NH (US);
Inventors:
Roshantha A. Chandraratna, Laguna Hills, CA (US);
Ethan Dmitrovsky, Hanover, NH (US);
Elizabeth Nowak, West Lebanon, NH (US);
Randolph Noelle, Plainfield, NH (US);
Martin E. Sanders, Santa Ana, CA (US);
Assignees:
Io Therapeutics, Inc., Houston, TX (US);
Trustees of Dartmouth College, Hanover, NH (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/192 (2006.01); A61K 31/4704 (2006.01); A61K 31/343 (2006.01); A61K 31/47 (2006.01); A61K 31/353 (2006.01); A61K 31/216 (2006.01);
U.S. Cl.
CPC ...
A61K 31/192 (2013.01); A61K 31/216 (2013.01); A61K 31/343 (2013.01); A61K 31/353 (2013.01); A61K 31/47 (2013.01); A61K 31/4704 (2013.01);
Abstract
The present specification provides RXR agonists with both remyelination promotion and immunomodulatory activities, compositions comprising such RXR agonists, and methods using such compounds and compositions to treat a demyelination-related disorder by both promoting remyelination of neurons and modulating the immune system.