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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10653634 B1

PDFFull Text
Expired
Date of Patent:
May. 19, 2020

Filed:

Dec. 18, 2019

Polymeric nanoparticulate formulation to enhance the oral bioavailability of dapoxetine

Applicants:

King Abdulaziz University, Jeddah, SA;

Virginia Commonwealth University, Richmond, VA (US);

Inventors:

Khalid M. El-Say, Jeddah, SA;

Osama A. A. Ahmed, Jeddah, SA;

Amir I. Mohamed, Jeddah, SA;

Abdelsattar M. Omar, Jeddah, SA;

Martin K. Safo, Richmond, VA (US);

Assignees:

King Abdulaziz University, Jeddah, SA;

Virginia Commonwealth University, Richmond, VA (US);

Attorney:

W & C IP

Primary Examiner:

Robert S Cabral

Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 31/138 (2006.01); A61P 15/12 (2006.01); A61K 9/19 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5169 (2013.01); A61K 9/19 (2013.01); A61K 9/5123 (2013.01); A61K 9/5192 (2013.01); A61K 31/138 (2013.01); A61P 15/12 (2018.01);
Abstract

Dapoxetine nanoparticles comprising zein and alpha lipoic acid (ALA) are provided. When present in zein-ALA loaded nanoparticles, dapoxetine exhibits increased bioavailability (compared to conventional formulations) when administered to subjects for the prevention or treatment of premature ejaculation (PE). Thus, lower doses are administered, and side effects are attenuated or eliminated.

Find Patent Forward Citations

El-Say, Khalid. (2020). Polymeric nanoparticulate formulation to enhance the oral bioavailability of dapoxetine (U.S. Patent No. 10653634). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10653634

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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