The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 19, 2020

Filed:

Jan. 31, 2018
Applicant:

Amorsa Therapeutics, Inc., Littleton, MA (US);

Inventors:

Alex Nivorozhkin, West Roxbury, MA (US);

Nelson Landrau, Marlborough, MA (US);

Assignee:

Amorsa Therapeutics, Inc., Littleton, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/20 (2006.01); A61K 31/135 (2006.01); A61K 31/13 (2006.01);
U.S. Cl.
CPC ...
A61K 9/2059 (2013.01); A61K 9/2013 (2013.01); A61K 9/2027 (2013.01); A61K 9/2031 (2013.01); A61K 9/2054 (2013.01); A61K 31/135 (2013.01); A61K 31/13 (2013.01);
Abstract

The present invention is directed to oral neuro-attenuating ketamine (NAKET) tablet formulations, and methods of administration, which ensure the steady release of a therapeutically effective concentration of ketamine from an oral tablet without neurologically toxic spikes in ketamine concentration. In particular, the present invention provides single layer oral tablet formulation of NAKET. In a specific embodiment, the NAKET tablet formulation, and methods of administration provide steady administration of NAKET to a subject for 24 hours or greater, for example, up to 36 hours, after a single administration event.


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