The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 19, 2020

Filed:

Jun. 29, 2018
Applicant:

Neostrata Company, Inc., Princeton, NJ (US);

Inventors:

Ruey J. Yu, Chalfont, PA (US);

Eugene J. Van Scott, Abington, PA (US);

Assignee:

NEOSTRATA COMPANY, INC., Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 8/64 (2006.01); C07K 5/02 (2006.01); C07K 5/062 (2006.01); C07K 5/078 (2006.01); C07K 5/072 (2006.01); A61K 31/07 (2006.01); A61K 8/67 (2006.01); A61K 38/05 (2006.01); A61Q 19/00 (2006.01); A61Q 19/08 (2006.01); C07K 5/065 (2006.01); C07K 5/06 (2006.01); A61K 9/00 (2006.01); A61Q 19/06 (2006.01); A61Q 5/00 (2006.01); A61Q 19/02 (2006.01);
U.S. Cl.
CPC ...
A61K 8/64 (2013.01); A61K 8/671 (2013.01); A61K 9/0014 (2013.01); A61K 31/07 (2013.01); A61K 38/05 (2013.01); A61Q 19/00 (2013.01); A61Q 19/06 (2013.01); A61Q 19/08 (2013.01); C07K 5/0202 (2013.01); C07K 5/0205 (2013.01); C07K 5/0207 (2013.01); C07K 5/0606 (2013.01); C07K 5/06026 (2013.01); C07K 5/06034 (2013.01); C07K 5/06043 (2013.01); C07K 5/06052 (2013.01); C07K 5/06069 (2013.01); C07K 5/06078 (2013.01); C07K 5/06113 (2013.01); C07K 5/06147 (2013.01); C07K 5/06156 (2013.01); C07K 5/06165 (2013.01); C07K 5/06191 (2013.01); A61K 2800/10 (2013.01); A61K 2800/92 (2013.01); A61Q 5/00 (2013.01); A61Q 19/007 (2013.01); A61Q 19/008 (2013.01); A61Q 19/02 (2013.01); Y02A 50/463 (2018.01);
Abstract

Methods of treating aging related skin changes and of increasing skin thickness with topical administration of N-acyldipeptide derivatives and retinol are described. Combinations of retinol and N-acyldipeptide derivatives, are therapeutically effective for increasing skin thickness, and for treating extrinsic and intrinsic aging and aging related skin changes, such as fine lines, wrinkles, photoaging, hyperpigmentation, laxity, age spots, lentigines, mottled skin, and cellulite.


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