The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 19, 2020

Filed:

Jan. 26, 2017
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Soroush Mohammad Mirzaei Zarandi, La Habra, CA (US);

Bruce J. Tromberg, Irvine, CA (US);

Thomas D. O'Sullivan, Laguna Hills, CA (US);

Siavash Sedighzadeh Yazdi, Irvine, CA (US);

Albert Cerussi, Cupertino, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/1455 (2006.01); A61B 5/145 (2006.01); A61B 5/024 (2006.01); A61B 5/08 (2006.01); A61B 5/00 (2006.01);
U.S. Cl.
CPC ...
A61B 5/14551 (2013.01); A61B 5/02416 (2013.01); A61B 5/0816 (2013.01); A61B 5/14546 (2013.01); A61B 5/7278 (2013.01);
Abstract

A low cost portable high speed quantitative system for diffuse optical spectroscopic imaging of human tissue. The hybrid system (CWFD) can measure absolute optical properties from 660 nm to 980 nm and recover all tissue chromophore concentrations. The standalone FD module can be utilized to measure scattering at every measurement and recover deoxygenated and oxygenated hemoglobin concentrations. The CW module can operate concurrently with the FD module to also measure water and lipid. The high temporal resolution and large signal-to-noise ratio of the CWFD system may be used to explore tissue oximetry, vascular occlusion, and paced breathing models to measure and analyze tissue hemodynamics response to changes in blood flow. Continuous monitoring of vasculature response to various modified blood perfusion conditions can provide information about local tissue metabolism and physiological state (dysfunction).


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