The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2020

Filed:

Jun. 15, 2018
Applicant:

Wayne State University, Detroit, MI (US);

Inventor:

Jian-Ping Jin, Chicago, IL (US);

Assignee:

Wayne State University, Detroit, MI (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); G01N 33/53 (2006.01); G01N 33/68 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6887 (2013.01); C07K 16/18 (2013.01); G01N 33/53 (2013.01); C07K 14/4702 (2013.01); C07K 2317/56 (2013.01); G01N 2333/4712 (2013.01); G01N 2800/32 (2013.01);
Abstract

Methods for detecting a cardiac condition in a human subject are provided according to aspects of the present invention which include providing an immunological reagent characterized by specific binding to: an N-terminal fragment of human cardiac troponin T (HcTnT-N69) or a neoepitope of human cardiac troponin T generated by removal of HcTnT-N69 from HcTnT (HcTnT-neo); contacting the immunological reagent with a biological sample of the human subject under binding conditions; and detecting binding of the immunological reagent with HcTnT-N69 or HcTnT-neo, wherein detection of HcTnT-N69 or HcTnT-neo in the biological sample is indicative of a cardiac condition in the subject. Antibodies and antigen binding fragments thereof characterized by specific binding to HcTnT-N69 or HcTnT-neo, or a variant of either thereof, are provided according to aspects of the present invention.


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Jin, Jian-Ping. (2020). Methods and compositions relating to anti-hctnt-n69 antibody for detection of cardiac disorders (U.S. Patent No. 10648987). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10648987

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