The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 12, 2020
Filed:
Jan. 06, 2017
Applicant:
Celgene Corporation, Summit, NJ (US);
Inventors:
Ellen Filvaroff, San Francisco, CA (US);
Antonia Lopez-Girona, San Diego, CA (US);
Gang Lu, San Diego, CA (US);
Assignee:
Celgene Corporation, Summit, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/454 (2006.01); A61P 35/02 (2006.01); G01N 33/574 (2006.01); C12Q 1/6886 (2018.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
G01N 33/574 (2013.01); A61K 31/454 (2013.01); A61K 45/06 (2013.01); C12Q 1/6886 (2013.01); G01N 33/57426 (2013.01); A61P 35/02 (2018.01); C12Q 2600/106 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/158 (2013.01); G01N 2800/52 (2013.01);
Abstract
A method of identifying a subject having cancer who is likely to be responsive to a treatment compound, comprising administering the treatment compound to the subject having the cancer; obtaining a sample from the subject; determining the level of a biomarker in the sample from the subject; and diagnosing the subject as being likely to be responsive to the treatment compound if the level of the biomarker in the sample of the subject changes as compared to a reference level of the biomarker; wherein the treatment compound is a compound of Formula I: