The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2020

Filed:

Mar. 22, 2016
Applicant:

Ipsen Biopharm Limited, Wrexham, GB;

Inventors:

Daniel Kwan, Abingdon, GB;

David Burgin, Abingdon, GB;

Stephen Gavin Hackett, Abingdon, GB;

Assignee:

IPSEN BIOPHARM LIMITED, Wrexham, GB;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/08 (2006.01); C07K 14/33 (2006.01); C12N 9/52 (2006.01);
U.S. Cl.
CPC ...
C12Y 304/24069 (2013.01); A61K 39/08 (2013.01); C07K 14/33 (2013.01); C12N 9/52 (2013.01); C07K 2319/00 (2013.01); C07K 2319/01 (2013.01); C07K 2319/21 (2013.01); C07K 2319/50 (2013.01);
Abstract

Chimeric clostridial neurotoxins in which the activation loop has been replaced by an activation loop from a different subtype within the same serotype. Methods of producing, activating, and using such neurotoxins. Compositions comprising such neurotoxins. Polynucleotides, vectors and cells for expressing such neurotoxins.


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