The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2020

Filed:

Apr. 18, 2019
Applicant:

Enzo Life Sciences, Inc., Farmingdale, NY (US);

Inventors:

Konrad T. Howitz, Allentown, PA (US);

Zhongda Zhang, Wynnewood, PA (US);

Anne Kisielewski, Wilmington, DE (US);

Elizabeth Dale, Allentown, PA (US);

Wayne Forrest Patton, Dix Hills, NY (US);

Assignee:

Enzo Life Sciences, Inc., Farmingdale, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/573 (2006.01); C12Q 1/37 (2006.01); C07D 493/10 (2006.01); C12Q 1/34 (2006.01); C07D 311/16 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/34 (2013.01); C07D 311/16 (2013.01); C07D 493/10 (2013.01); C12Y 305/01098 (2013.01); G01N 2333/98 (2013.01);
Abstract

Provided is a compound that comprises the structure: where SIG is a signaling molecule and Ris a formyl, a succinyl, a methyl succinyl, or a myristoyl. Also provided is a kit is provided that comprises the above compound, with instructions for determining the presence of the enzyme. Additionally, a method is provided for determining whether a sample has an enzyme that removes a succinyl, a methyl succinyl, a formyl, or a myristoyl moiety from an ε-amino of a lysine. Also provided is a method of determining whether a molecule inhibits an enzyme that removes a succinyl, a methyl succinyl, a formyl, or a myristoyl moiety from an ε-amino of a lysine.


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