The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 12, 2020
Filed:
Nov. 22, 2017
Applicant:
Regents of the University of Minnesota, Minneapolis, MN (US);
Inventors:
Beau R. Webber, Minneapolis, MN (US);
Mark J. Osborn, Minneapolis, MN (US);
Jakub Tolar, Minneapolis, MN (US);
Bruce R. Blazar, Golden Valley, MN (US);
Assignee:
REGENTS OF THE UNIVERSITY OF MINNESOTA, Minneapolis, MN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/90 (2006.01); C12N 5/077 (2010.01); C12N 5/074 (2010.01); C12N 5/071 (2010.01); C07K 14/78 (2006.01); C12N 5/0789 (2010.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01); C07K 14/78 (2013.01); C12N 5/0629 (2013.01); C12N 5/0647 (2013.01); C12N 5/0652 (2013.01); C12N 5/0656 (2013.01); C12N 5/0696 (2013.01); C12N 15/102 (2013.01); C07K 2319/81 (2013.01); C12N 2310/20 (2017.05); C12N 2500/38 (2013.01); C12N 2500/90 (2013.01); C12N 2501/155 (2013.01); C12N 2501/727 (2013.01); C12N 2502/28 (2013.01); C12N 2506/1307 (2013.01); C12N 2506/45 (2013.01); C12N 2510/00 (2013.01); C12N 2533/54 (2013.01); C12N 2760/18843 (2013.01);
Abstract
Methods of gene correction, methods of generating induced pluripotent stem cells (iPSCs), and methods of deriving multi-lineage cell types with therapeutic value. In some embodiments, the gene correction affects the expression and/or function of the functional type VII collagen protein (C7).