The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 12, 2020
Filed:
Sep. 10, 2012
Applicants:
Yongzhang Luo, Beijing, CN;
Peng Liu, Beijing, CN;
Xinan LU, Beijing, CN;
Yang Chen, Beijing, CN;
Yan Fu, Beijing, CN;
Guodong Chang, Beijing, CN;
Daifu Zhou, Beijing, CN;
Inventors:
Yongzhang Luo, Beijing, CN;
Peng Liu, Beijing, CN;
Xinan Lu, Beijing, CN;
Yang Chen, Beijing, CN;
Yan Fu, Beijing, CN;
Guodong Chang, Beijing, CN;
Daifu Zhou, Beijing, CN;
Assignees:
Tsinghua University, Beijing, CN;
Beijing Protgen Ltd., Beijing, CN;
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); C12N 9/14 (2006.01); C07K 14/475 (2006.01); C12Q 1/00 (2006.01); A61K 47/60 (2017.01);
U.S. Cl.
CPC ...
C12N 9/14 (2013.01); A61K 38/18 (2013.01); A61K 47/60 (2017.08); C07K 14/475 (2013.01); C12Q 1/00 (2013.01);
Abstract
The present invention discloses a new anti-tumor medicament comprising a mutant of endostatin. The mutant comprises a mutation in the ATP-binding site of endostatin and has a decreased ATPase activity and an increased anti-angiogenesis activity.