The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2020

Filed:

Aug. 12, 2016
Applicants:

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

University of Washington, Seattle, WA (US);

Inventors:

Peter A. Cohen, Scottsdale, AZ (US);

Sandra J. Gendler, Scottsdale, AZ (US);

Latha B. Pathangey, Scottsdale, AZ (US);

Dustin B. McCurry, Phoenix, AZ (US);

Jessica E. Gorman, Scottsdale, AZ (US);

Mary L. Disis, Renton, WA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0783 (2010.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0636 (2013.01); A61K 39/0011 (2013.01); A61K 2039/5158 (2013.01); C12N 2501/22 (2013.01); C12N 2501/2307 (2013.01); C12N 2501/51 (2013.01); C12N 2501/515 (2013.01);
Abstract

This document provides methods and materials for expanding antigen-specific T cells (e.g., antigen-specific CD4T cells and/or antigen-specific CD8T cells) in culture. For example, methods and materials for performing a polyclonal stimulation step for a particular duration (e.g., from about 1 hour to about 48 hours) to increase the expansion of T cells having a desired antigen specificity are provided.


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