The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 12, 2020
Filed:
Apr. 21, 2015
Applicant:
Université DE Montréal, Montréal, CA;
Inventors:
Guy Sauvageau, Montréal, CA;
Yves Gareau, Notre-Dame-de-I'lle Perrot, CA;
Stéphane Gingras, Montreal, CA;
Assignee:
UNIVERSITÉDE MONTRÉAL, Montréal, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/14 (2006.01); A61K 35/28 (2015.01); C07D 471/04 (2006.01); A61K 31/5377 (2006.01); A61K 31/519 (2006.01); A61K 31/4545 (2006.01); A61K 45/06 (2006.01); A61K 31/444 (2006.01); A61P 43/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/14 (2013.01); A61K 31/444 (2013.01); A61K 31/4545 (2013.01); A61K 31/519 (2013.01); A61K 31/5377 (2013.01); A61K 35/28 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); A61P 43/00 (2018.01); C07D 471/04 (2013.01);
Abstract
Compounds of general formula or salts or prodrugs thereof, are provided and described herein. The compounds are useful to expand hematopoietic stem cell and/or hematopoietic progenitor cell populations. Particularly, the hematopoietic cells are human cells. The compounds are also useful in the medical treatment of hematopoietic disorder/malignancy, an autoimmune disease and/or an inherited immune-deficient disease in a subject.