The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2020

Filed:

Jun. 24, 2016
Applicants:

The Trustees of Columbia University IN the City of New York, New York, NY (US);

The Board of Trustees of the University of Illinois, Urbana, IL (US);

Inventors:

Gregory R. J. Thatcher, Chicago, IL (US);

Isaac Thomas Schiefer, Chicago, IL (US);

Ottavio Arancio, New York, NY (US);

Mauro Fa, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01); C07D 409/12 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 495/04 (2006.01); C07D 303/48 (2006.01); C07D 405/12 (2006.01);
U.S. Cl.
CPC ...
C07D 417/12 (2013.01); C07D 303/48 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 409/12 (2013.01); C07D 417/14 (2013.01); C07D 495/04 (2013.01);
Abstract

The invention provides for novel cysteine protease inhibitors and compositions comprising novel cysteine protease derivatives. The invention further provides for methods for treatment of neurodegenerative diseases comprising administration novel cysteine protease inhibitors or compositions comprising novel cysteine protease inhibitors. In some embodiments, the cysteine protease inhibitors are calpain inhibitors.


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