IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10647705 B1

PDFFull Text
Date of Patent:
May. 12, 2020

Filed:

Nov. 12, 2018

Substituted biaryl compounds as indoleamine 2,3-dioxygenase (ido) inhibitors

Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Yongxin Han, Needham, MA (US);

Abdelghani Achab, Melrose, MA (US);

Yongqi Deng, Newton, MA (US);

Xavier Fradera, Brookline, MA (US);

Craig Gibeau, Holliston, MA (US);

Brett A. Hopkins, Stoughton, MA (US);

Derun Li, West Roxbury, MA (US);

Kun Liu, Needham, MA (US);

Meredeth A. McGowan, Boston, MA (US);

Nunzio Sciammetta, Sudbury, MA (US);

David Sloman, Brookline, MA (US);

Catherine White, Newton Center, MA (US);

Hongjun Zhang, Boston, MA (US);

Hua Zhou, Acton, MA (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:

Yong Zhao

Anna L. Cocuzzo

Primary Examiner:

Rei Tsang Shiao

Int. Cl.
CPC ...
C07D 405/10 (2006.01); A61K 31/4523 (2006.01); A61K 45/06 (2006.01); C07D 471/04 (2006.01); A61K 31/437 (2006.01); A61K 31/506 (2006.01); A61K 31/4155 (2006.01); C07D 305/08 (2006.01); A61K 31/337 (2006.01); C07D 417/10 (2006.01); A61K 31/427 (2006.01); A61K 31/41 (2006.01); A61K 31/4245 (2006.01); A61K 31/4184 (2006.01); C07D 405/14 (2006.01); A61K 31/444 (2006.01); A61K 31/513 (2006.01); C07D 413/04 (2006.01); C07D 401/04 (2006.01); C07D 213/56 (2006.01); A61K 31/4418 (2006.01); C07D 417/14 (2006.01); A61K 31/501 (2006.01); C07D 241/12 (2006.01); A61K 31/4965 (2006.01); A61K 31/4427 (2006.01); C07D 263/32 (2006.01); A61P 37/00 (2006.01); C07D 231/12 (2006.01); A61P 35/00 (2006.01); C07D 413/10 (2006.01); C07D 401/12 (2006.01); C07D 405/04 (2006.01); A61P 31/00 (2006.01); C07D 209/46 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 405/10 (2013.01); A61K 31/337 (2013.01); A61K 31/41 (2013.01); A61K 31/4155 (2013.01); A61K 31/4184 (2013.01); A61K 31/427 (2013.01); A61K 31/4245 (2013.01); A61K 31/437 (2013.01); A61K 31/444 (2013.01); A61K 31/4418 (2013.01); A61K 31/4427 (2013.01); A61K 31/4523 (2013.01); A61K 31/4965 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 31/513 (2013.01); A61K 45/06 (2013.01); A61P 31/00 (2018.01); A61P 35/00 (2018.01); A61P 37/00 (2018.01); C07D 209/46 (2013.01); C07D 213/56 (2013.01); C07D 231/12 (2013.01); C07D 241/12 (2013.01); C07D 263/32 (2013.01); C07D 305/08 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 405/04 (2013.01); C07D 405/14 (2013.01); C07D 413/04 (2013.01); C07D 413/10 (2013.01); C07D 413/14 (2013.01); C07D 417/10 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01);
Abstract

Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of a composition in the potential treatment or prevention of an IDO-associated disease or disorder.

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