The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 12, 2020
Filed:
Oct. 18, 2017
Applicant:
Cellcentric Ltd, Cambridge, Cambridgeshire, GB;
Inventors:
Neil Anthony Pegg, Cambridge, GB;
David Michel Adrien Taddei, Nottingham, GB;
Jonathan Shannon, Nottingham, GB;
Silvia Paoletta, Nottingham, GB;
Ting Qin, Nottingham, GB;
Gareth Harbottle, Nottingham, GB;
Assignee:
CELLCENTRIC LTD, Cambridge, Cambridgeshire, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 403/14 (2006.01); A61P 35/00 (2006.01); C07D 401/04 (2006.01); A61K 9/20 (2006.01); C07D 403/04 (2006.01); A61K 9/00 (2006.01); A61K 31/4184 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 403/14 (2013.01); A61K 9/0019 (2013.01); A61K 9/2018 (2013.01); A61K 9/2059 (2013.01); A61K 31/4184 (2013.01); A61P 35/00 (2018.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); A61K 45/06 (2013.01);
Abstract
A compound which is a benzimidazole of formula (I): wherein X is a 5-membered heteroaryl group selected from the following: or a pharmaceutically acceptable salt thereof. The compound has activity in modulating the activity of p300 and/or CBP and is used to treat cancer, particularly prostate cancer.