The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2020

Filed:

Dec. 22, 2017
Applicant:

Cytonome/st, Llc, Bedford, MA (US);

Inventors:

Erin Koksal, Cambridge, MA (US);

Jack Lapidas, Southborough, MA (US);

Jeanne Tanner, Winchester, MA (US);

Assignee:

CYTONOME/ST, LLC, Bedford, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G01N 35/00 (2006.01); G01N 33/48 (2006.01); G01N 1/00 (2006.01); G01N 1/10 (2006.01); G01N 15/14 (2006.01); G01N 29/22 (2006.01); G01N 15/10 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502761 (2013.01); B01L 3/502776 (2013.01); G01N 15/1404 (2013.01); G01N 15/1484 (2013.01); G01N 29/22 (2013.01); B01L 2200/0636 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0864 (2013.01); B01L 2400/0436 (2013.01); B01L 2400/0496 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/142 (2013.01); G01N 2015/149 (2013.01);
Abstract

A microfluidic chip assembly having a plurality of microfluidic flow channels is provided. Each channel has a switching region. The microfluidic chip may further include at least one surface acoustic wave generator configured to generate a pressure pulse in the switching regions of the channels to selectively deflect particles in the flow. Attenuation elements and/or channel configurations may be used to prevent acoustic signals from interfering with neighboring switching regions. Alternatively, a microfluidic particle processing system may include a microfluidic chip assembly, a particle processing instrument, and a coupling element. The surface acoustic wave generator may be provided on the particle processing instrument. The microfluidic chip assembly may be configured for operative engagement, via the coupling element, with the particle processing instrument. The coupling element may transmit acoustic energy from the surface acoustic wave generator to the switching regions and/or to focusing regions of the flow channels.


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