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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10646619 B1

PDFFull Text
Date of Patent:
May. 12, 2020

Filed:

Dec. 14, 2018

Bone substitute material

Applicant:

Geistlich Pharma Ag, Wolhusen, CH;

Inventors:

Claudio Zihlmann, Lucerne, CH;

Michael Bufler, Reinach, CH;

Assignee:

GEISTLICH PHARMA AG, Wolhusen, CH;

Attorney:

Rothwell, Figg, Ernst & Manbeck, P.C.

Primary Examiner:

Tracy Liu

Int. Cl.
CPC ...
A61L 27/12 (2006.01); A61L 27/32 (2006.01); A61K 33/42 (2006.01); A61K 9/14 (2006.01); A61K 9/16 (2006.01); A61L 27/42 (2006.01); A61L 27/58 (2006.01); A61L 24/00 (2006.01); A61L 27/36 (2006.01); A61L 27/50 (2006.01);
U.S. Cl.
CPC ...
A61L 27/425 (2013.01); A61L 27/12 (2013.01); A61L 27/32 (2013.01); A61L 27/58 (2013.01); A61L 24/0063 (2013.01); A61L 27/3608 (2013.01); A61L 27/50 (2013.01); A61L 2400/12 (2013.01); A61L 2400/18 (2013.01); A61L 2430/02 (2013.01);
Abstract

A biphasic calcium phosphate/hydroxyapatite (CAP/HAP) bone substitute material having a sintered CAP core and at least one closed epitactically grown layer of nanocrystalline HAP deposited on the external surface of the sintered CAP core, whereby the epitactically grown nanocrystals have the same size and morphology as human bone mineral, wherein the closed epitactically grown layer of nanocrystalline HAP deposited on the external surface of the sintered CAP core has a non-homogeneous external surface comprising individual clusters of flat crystal platelets consisting of epitactically grown HAP nanocrystals and coarse areas between the individual clusters, whereby the percentage of the coarse areas between the individual clusters as measured by SEM is at least 20% of the total surface, which material shows an increased capacity to induce bone formation, and a process of preparation thereof.

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