The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 12, 2020
Filed:
Jun. 24, 2014
GE Healthcare Limited, Chalfont St Giles, Buckinghamshire, GB;
Imperial Innovations Limited, London, Greater London, GB;
Duncan Robert R. Hiscock, Amersham, GB;
Eric Aboagye, London, GB;
Peter Iveson, Amersham, GB;
Quang-De Nguyen, London, GB;
Susan Hoppmann, Amersham, GB;
Sebastian Trousil, London, GB;
Maciej Kaliszczak, London, GB;
Giampaolo Tomasi, London, GB;
IMPERIAL INNOVATIONS LIMITED, London, GB;
GE HEALTHCARE LIMITED, Buckinghamshire, GB;
Abstract
A method of use of an isolated polypeptide conjugated with a radionuclide, wherein the isolated polypeptide binds specifically to HER2, or a variant thereof is described. The method is for monitoring the response to HSP90 inhibition and comprises the use of the isolated polypeptide conjugated with 18F. The application also describes the use of an isolated polypeptide conjugated with 18F, wherein the isolated polypeptide binds specifically to HER2 or variants thereof, as an imaging agent to monitor uptake thereof to measure HSP90 inhibition.