The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2020

Filed:

Dec. 23, 2015
Applicant:

Apitope International NV, Diepenbeek, BE;

Inventors:

Lotta Jansson, Diepenbeek, BE;

Keith Martin, Chepstow Gwent, GB;

David Wraith, Chepstow Gwent, GB;

Andrea Jahraus, Diepenbeek, BE;

Kathleen Vrolix, Diepenbeek, BE;

Assignee:

APITOPE INTERNATIONAL NV, Diepenbeek, BE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/04 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01); A61K 48/00 (2006.01); A61K 39/00 (2006.01); C07K 14/72 (2006.01); A01K 67/027 (2006.01); A61K 38/17 (2006.01); A61P 5/14 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0066 (2013.01); A01K 67/027 (2013.01); A61K 38/1796 (2013.01); A61K 39/0005 (2013.01); A61K 48/0083 (2013.01); A61P 5/14 (2018.01); C07K 14/723 (2013.01); A01K 2207/05 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0325 (2013.01); A61K 2039/577 (2013.01);
Abstract

The present invention provides a composition which comprises the following Thyroid Stimulating Hormone Receptor (TSHR) peptides: (i) all or part of the amino acid sequence KKKKYVSIDVTLQQLESHKKK (SEQ ID NO: 1), or a part thereof, or a sequence having at least 60% sequence identity to SEQ ID NO:1; and (ii) all or part of the amino acid sequence GLKMFPDLTKVYSTD (SEQ ID NO: 2), or a part thereof, or a sequence having at least 60% sequence identity to SEQ ID NO:2. The present invention also relates to the use of such a composition for the prevention or suppression of activating autoantibody formation in Graves' disease.


Find Patent Forward Citations

Loading…