The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 12, 2020
Filed:
Oct. 13, 2017
Applicant:
Sam Chun Dang Pharm. Co., Ltd., Hwaseong-si, Gyeonggi-do, KR;
Inventors:
Guang-Jin Im, Ansan-si, KR;
Byung-Jhip Ha, Icheon-si, KR;
Na-Won Park, Suwon-si, KR;
Yong-Seop Park, Suwon-si, KR;
Assignee:
SAM CHUN DANG PHARM. CO., LTD., Hwasseong-si, Gyeonggi-do, KR;
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 9/00 (2006.01); A61K 47/12 (2006.01); A61K 47/26 (2006.01);
U.S. Cl.
CPC ...
A61K 38/179 (2013.01); A61K 9/0048 (2013.01); A61K 47/12 (2013.01); A61K 47/26 (2013.01);
Abstract
Provided is an ophthalmic pharmaceutical composition having a certain pH, comprising aflibercept as an active ingredient and an acetate salt buffering agent, wherein the composition is free of an ionic tonicity agent, remarkably reduces the formation of dimeric and multimeric impurities, and maintains the biological activity in a high level for a long time, under the accelerated and stress conditions as well as under the cold storage condition.