The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2020

Filed:

Apr. 16, 2015
Applicant:

Genovie Ab, Karlskrona, SE;

Inventors:

Reagan Micheal Jarvis, Sydney, AU;

Magnus Thörn, Uppsala, SE;

Assignee:

GENOVIE AB, Karlskrona, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); G01N 33/569 (2006.01); C12N 5/0783 (2010.01); A61K 9/08 (2006.01); A61K 47/02 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A61K 9/08 (2013.01); A61K 47/02 (2013.01); C12N 5/0637 (2013.01); G01N 33/56972 (2013.01); G01N 2333/70517 (2013.01);
Abstract

The present invention relates to composition comprising an isolated CD8Treg cell population, wherein the Treg cells have signatures for i) identifying that the T-cells are CD8regulatory Tcells, ii) identifying that the Treg cells are tissue type tropic, i.e they can migrate to the diseased tissue, iii) optionally identifying that the Treg cells are tropic with respect to the diseased tissue, i.e. they are homing cells, iv) identifying that the Treg cells are emigrant cells, i.e. they originate from the target tissue, and v) optionally identifying that the Treg cells are capable of being retained in the target tissue and optionally one or more X-signatures and/or one or more Y-signatures.


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