The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2020

Filed:

Aug. 07, 2017
Applicant:

Kissei Pharmaceutical Co., Ltd., Matsumoto-shi, Nagano, JP;

Inventors:

Takuro Dan, Tokyo, JP;

Hideomi Takahashi, Tokyo, JP;

Yu Kuramochi, Tokyo, JP;

Assignee:

KISSEI PHARMACEUTICAL CO., LTD., Matsumoto-shi, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61P 15/00 (2006.01); A61P 29/00 (2006.01); C07D 495/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61P 15/00 (2018.01); A61P 29/00 (2018.01);
Abstract

An object of the present invention is to provide pharmaceutical agents that reduce risk for decrease in bone mineral density due to their effect of reducing estrogen levels and exert excellent therapeutic effects on endometriosis. The present invention relates to pharmaceutical compositions for treating endometriosis comprising 3-[2-fluoro-5-(2,3-difluoro-6-methoxybenzyloxy)-4-methoxyphenyl]-2,4-dioxo-1,2,3,4-tetrahydrothieno[3,4-d]pyrimidine-5-carboxylic acid or a pharmaceutically acceptable salt thereof, which are administered orally once a day at a daily dose of between 50 mg and 75 mg calculated as a free form.


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