The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2020

Filed:

Jan. 26, 2016
Applicant:

Foreland Pharma Co., Ltd., Beijing, CN;

Inventors:

Qi Ji, Beijing, CN;

Zhenjian Du, Beijing, CN;

Xingmin Zhang, Beijing, CN;

Lei Wang, Beijing, CN;

Congmin Gao, Beijing, CN;

Longlong Gong, Beijing, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 471/14 (2006.01); A61K 31/4745 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4745 (2013.01); A61P 35/00 (2018.01); C07D 471/04 (2013.01); C07D 471/14 (2013.01);
Abstract

The present invention relates to the crystal form of imidazolone type compounds, and a preparation method, pharmaceutical composition and use thereof, and falls within the field of pharmaceutical compound crystals. The crystal form provided by the present invention has a good stability, comprising good stability under the three extreme conditions of high temperature, high humidity and strong illumination, and can also maintain a good stability during the tablet compressing process. The crystal form provided by the present invention has good absorption and metabolism properties in vivo, comprising the drug concentration of blood, the drug concentration-time curve AUC, the half-life period, etc. In addition, the dissolving rate of the crystal form of the present invention is improved, wherein same is beneficial for the applications thereof in preparations.


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