The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2020

Filed:

May. 01, 2019
Applicant:

National Cancer Center, Gyeonggi-do, KR;

Inventors:

Seok Gu Kang, Gyeonggi-do, KR;

Jong Hee Chang, Seoul, KR;

Eui Hyun Kim, Seoul, KR;

Ji Hyun Lee, Gyeonggi-do, KR;

Yun Hee Jo, Seoul, KR;

Junseong Park, Seoul, KR;

Jin Kyoung Shim, Seoul, KR;

Soo Youl Kim, Gyeonggi-do, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/155 (2006.01); A61K 31/11 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/155 (2013.01); A61K 31/11 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01);
Abstract

The present invention relates to a pharmaceutical composition for inhibiting growth of cancer stem cells, containing an aldehyde inhibitor and a biguanide-based compound. The pharmaceutical composition according to the present invention contains a combination of an aldehyde inhibitor and a biguanide-based compound, which can effectively inhibit the growth of cancer stem cells such as neurospheres and can also inhibit the proliferation, invasion and metastasis of cancer cells, thereby preventing and/or treating cancer such as brain cancer.


Find Patent Forward Citations

Loading…