The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2020
Filed:
Jul. 17, 2015
Applicants:
Vib Vzw, Ghent, BE;
Vrije Universiteit Brussel, Brussels, BE;
Inventors:
Assignees:
VIB VZW, Ghent, BE;
Vrije Universiteit Brussel, Brussels, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); G01N 33/49 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6845 (2013.01); G01N 33/6854 (2013.01); G01N 33/6857 (2013.01); G01N 33/492 (2013.01); G01N 33/4915 (2013.01);
Abstract
The application relates to the field of structural biology. More specifically, the disclosure relates to methods for the identification and characterization of biomolecular tools allowing the selective recognition and/or stabilization of distinct conformational states of protein complexes, including transient protein-protein interactions and protein-nucleic acid complexes. Such tools can then be used for purification purposes, crystallization and structure determination of these stabilized protein complexes, for drug discovery, as research tools, as well as for diagnosis and treatment of diseases.