The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2020
Filed:
May. 03, 2018
Applicant:
The Florida International University Board of Trustees, Miami, FL (US);
Inventor:
Barry P. Rosen, Coral Gables, FL (US);
Assignee:
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES, Miami, FL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/96 (2006.01); C12Q 1/02 (2006.01); C12Q 1/689 (2018.01); C12Q 1/18 (2006.01); G01N 33/84 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/02 (2013.01); C12Q 1/18 (2013.01); C12Q 1/689 (2013.01); G01N 33/84 (2013.01); C12Q 2600/142 (2013.01);
Abstract
Disclosed are methods of detecting organic arsenicals using genetically modified cells containing an arsR gene that encodes an AfArsR (As(III)-responsive repressor) protein and an arsenical resistance operon operably linked to a green fluorescent protein gene. The cell can produce a green fluorescent protein and fluoresce in the presence of trivalent organic arsenic. Trivalent organic arsenics can be one or more of phenylarsenite, travlent roaxarsone, and methylarsenite.