The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2020
Filed:
Dec. 19, 2014
Novartis Ag, Basel, CH;
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Gregory Beatty, Philadelphia, PA (US);
Boris Engels, Cambridge, MA (US);
Neeraja Idamakanti, Cambridge, MA (US);
Carl H. June, Merion Station, PA (US);
Andreas Loew, Cambridge, MA (US);
Huijuan Song, Shanghai, CN;
Qilong Wu, Shanghai, CN;
Novartis AG, Basel, CH;
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Abstract
Provided are compositions and methods for treating diseases associated with expression of mesothelin. Also provided are a chimeric antigen receptor(CAR) specific to mesothelin, vectors encoding the same, and recombinant T cells comprising the mesothelin CAR. Further provided are methods of administering a genetically modified T cell expressing a CAR that comprises a mesothelin binding domain.