The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 05, 2020

Filed:

Mar. 06, 2018
Applicant:

Pfizer Inc., New York, NY (US);

Inventors:

Bianca Ahrens, Munich, DE;

Sangita M. Baxi, San Diego, CA (US);

Timothy Scott Fisher, San Diego, CA (US);

Richard Michael Jerome, East Hampstead, NH (US);

Kathrin Ladetzki-Baehs, Planegg, DE;

Theodore Lawrence Oliphant, Galesburg, MI (US);

Leslie Lynne Sharp, San Diego, CA (US);

Michael Tesar, Augsberg, DE;

Libbey Anne Yates, Dardenne Prairie, MI (US);

Moritz Zulley, Munich, DE;

Assignee:

Pfizer Inc., New York, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61K 38/02 (2006.01); C12N 5/07 (2010.01); C12N 15/62 (2006.01); A61P 35/00 (2006.01); A61K 45/06 (2006.01); C07K 16/30 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2878 (2013.01); A61K 38/02 (2013.01); A61K 39/39558 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07K 16/2887 (2013.01); C07K 16/30 (2013.01); C12N 5/06 (2013.01); C12N 15/62 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/21 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/52 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/567 (2013.01); C07K 2317/74 (2013.01); C07K 2317/75 (2013.01); C07K 2317/92 (2013.01);
Abstract

The present disclosure provides isolated binding molecules that bind to human 4-1BB, nucleic acid molecules encoding an amino acid sequence of the binding molecules, vectors comprising the nucleic acid molecules, host cells containing the vectors, methods of making the binding molecules, pharmaceutical compositions containing the binding molecules, and methods of using the binding molecules or compositions.


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