The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2020
Filed:
Aug. 18, 2016
Applicant:
National University Corporation Hokkaido University, Hokkaido, JP;
Inventors:
Ayato Takada, Hokkaido, JP;
Reiko Yoshida, Hokkaido, JP;
Wakako Furuyama, Hokkaido, JP;
Hiroko Miyamoto, Hokkaido, JP;
Junki Maruyama, Hokkaido, JP;
Shigeru Iida, Tokyo, JP;
Shinya Ogawa, Tokyo, JP;
Assignee:
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY, Hokkaido, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/10 (2006.01); A61P 31/14 (2006.01); G01N 33/569 (2006.01); C12N 5/10 (2006.01); A61K 39/395 (2006.01); C07K 1/16 (2006.01); C12N 15/02 (2006.01); C12N 15/09 (2006.01);
U.S. Cl.
CPC ...
C07K 16/10 (2013.01); A61K 39/395 (2013.01); A61P 31/14 (2018.01); C07K 1/16 (2013.01); C12N 5/10 (2013.01); C12N 15/02 (2013.01); C12N 15/09 (2013.01); G01N 33/569 (2013.01); C07K 2317/30 (2013.01); C07K 2317/33 (2013.01); C07K 2317/565 (2013.01); C07K 2317/90 (2013.01);
Abstract
There has been a need for a neutralizing monoclonal antibody which is useful for antibody therapy effective against ebolavirus. The present invention provides a monoclonal antibody or an antigen-binding fragment thereof, which recognizes an internal fusion loop of ebolavirus GP and is capable of neutralizing the biological activity of ebolavirus.