The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2020
Filed:
Oct. 16, 2015
Applicants:
University of Virginia Patent Foundation, Charlottesville, VA (US);
The University of Chicago, Chicago, IL (US);
Inventors:
Zygmunt S. Derewenda, Charlottesville, VA (US);
Daniel A. Engel, Charlottesville, VA (US);
Anthony Kossiakoff, Chicago, IL (US);
Elena K. Davydova, Chicago, IL (US);
Mateusz Jaskolowski, Kargoszyn, PL;
Assignees:
University of Virginia Patent Foundation, Charlottesville, VA (US);
The University of Chicago, Chicago, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/10 (2006.01); C12Q 1/70 (2006.01); A61K 39/42 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
C07K 16/10 (2013.01); A61K 39/42 (2013.01); C12Q 1/701 (2013.01); G01N 33/56983 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/92 (2013.01); C12N 2760/14111 (2013.01); C12N 2760/14122 (2013.01); G01N 2333/08 (2013.01);
Abstract
This disclosure is directed to compositions and methods for utilizing the boundaries of the C-terminal domains of Nucleoprotein from Zaire Ebola virus as highly stable recombinant protein antigens to generate antibodies for diagnosis and treatment of Ebola virus infection.