The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 05, 2020

Filed:

Oct. 10, 2018
Applicant:

Apogenix Ag, Heidelberg, DE;

Inventors:

Oliver Hill, Neckarsteinach, DE;

Christian Gieffers, Dossenheim, DE;

Meinolf Thiemann, Schriesheim, DE;

Assignee:

APOGENIX AG, Heidelberg, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/525 (2006.01); C12N 15/62 (2006.01); C12N 15/79 (2006.01); C07K 14/705 (2006.01); C07K 16/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/525 (2013.01); C07K 14/70575 (2013.01); C07K 14/70578 (2013.01); C07K 16/00 (2013.01); C12N 15/62 (2013.01); C12N 15/79 (2013.01); A61K 38/00 (2013.01); C07K 2317/41 (2013.01); C07K 2317/52 (2013.01); C07K 2317/55 (2013.01); C07K 2319/00 (2013.01); C07K 2319/22 (2013.01); C07K 2319/30 (2013.01); C07K 2319/32 (2013.01); C07K 2319/35 (2013.01); C07K 2319/74 (2013.01);
Abstract

The present invention refers to single-chain fusion proteins comprising three soluble TNF superfamily (TNFSF) cytokine domains and nucleic acid molecules encoding these fusion proteins. The fusion proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.


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