The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2020
Filed:
Jul. 14, 2015
Applicant:
Centrax International, Inc., South San Francisco, CA (US);
Inventors:
Jinfu Yang, South San Francisco, CA (US);
Jian James Cen, Cixi, CN;
Xiaoqing Michelle Fan, South San Francisco, CA (US);
Assignee:
CENTRAX INTERNATIONAL, INC., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 5/06 (2006.01); C07K 5/065 (2006.01); C07K 5/02 (2006.01); C07K 5/097 (2006.01); C07K 5/083 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 5/06078 (2013.01); C07K 5/0202 (2013.01); C07K 5/0806 (2013.01); C07K 5/0821 (2013.01); A61K 38/00 (2013.01);
Abstract
The present disclosure relates to novel compounds and pharmaceutical compositions thereof which are useful as inhibitors of proteasomes. The compounds provided herein have improved proteasome potency and selectivity, and increased aqueous solubility, and are useful in treating various conditions or diseases associated with proteasomes.