The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 05, 2020

Filed:

Aug. 31, 2016
Applicant:

Industry-university Cooperation Foundation Hanyang University Erica Campus, Ansan-si, KR;

Inventors:

Pil Seok Chae, Ansan-si, KR;

Kyung Ho Cho, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 15/18 (2006.01); C07K 1/14 (2006.01); C07K 14/705 (2006.01); C07K 14/72 (2006.01);
U.S. Cl.
CPC ...
C07H 15/18 (2013.01); C07K 1/145 (2013.01); C07K 14/705 (2013.01); C07K 14/723 (2013.01);
Abstract

The present invention relates to a mesitylene-cored amphiphile, a method of preparing the same and a method of extraction, solubilization, stabilization, crystallization or analysis of a membrane protein using the same. When a mesitylene-cored compound according to the present invention is used, membrane proteins can be stored in a stable conformation for a long time in an aqueous solution in comparison with conventional compounds, by which the membrane proteins are usable in both functional and structural analyses thereof. The functional and structural analyses of membrane proteins are one of the fields that are most spotlighted in current biology and chemistry. The present invention can be used to research on a protein structure closely related to new drug development.


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