The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 05, 2020

Filed:

Jun. 11, 2012
Applicants:

Yan Feng, Shanghai, CN;

Mauro Fa, New York, NY (US);

Ottavio Arancio, New York, NY (US);

Shixian Deng, White Plains, NY (US);

Donald W. Landry, New York, NY (US);

Yitshak Francis, New York, NY (US);

Inventors:

Yan Feng, Shanghai, CN;

Mauro Fa, New York, NY (US);

Ottavio Arancio, New York, NY (US);

Shixian Deng, White Plains, NY (US);

Donald W. Landry, New York, NY (US);

Yitshak Francis, New York, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); C07C 235/64 (2006.01); C07C 323/67 (2006.01); C07C 323/42 (2006.01); C07D 213/82 (2006.01); C07D 213/75 (2006.01); C07C 235/56 (2006.01); C07C 237/40 (2006.01); C07D 239/52 (2006.01); C07D 333/38 (2006.01); C12Q 1/48 (2006.01); C07C 323/44 (2006.01); C07C 323/60 (2006.01);
U.S. Cl.
CPC ...
C07C 235/64 (2013.01); C07C 235/56 (2013.01); C07C 237/40 (2013.01); C07C 323/42 (2013.01); C07C 323/44 (2013.01); C07C 323/60 (2013.01); C07C 323/67 (2013.01); C07D 213/75 (2013.01); C07D 213/82 (2013.01); C07D 239/52 (2013.01); C07D 333/38 (2013.01); C12Q 1/48 (2013.01); C07C 2601/08 (2017.05); G01N 2500/04 (2013.01); G01N 2800/2814 (2013.01);
Abstract

The invention provides for a method for screening compounds that bind to and modulate a histone acetyltransferase protein. The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a HAT-activating compound to a subject.


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