The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2020
Filed:
Mar. 05, 2018
United Kingdom Research and Innovation, Swindon, GB;
President and Fellows of Harvard College, Cambridge, MA (US);
Andrew David Griffiths, Strasbourg, FR;
David A. Weitz, Cambridge, MA (US);
Darren Roy Link, Lexington, MA (US);
Keunho Ahn, Boston, MA (US);
Jerome Bibette, Paris, FR;
President and Fellows of Harvard College, Cambridge, MA (US);
United Kingdom Research and Innovation, Swindon, GB;
Abstract
The invention describes a method for isolating one or more genetic elements encoding a gene product having a desired activity, comprising the steps of: (a) compartmentalising genetic elements into microcapsules; and (b) sorting the genetic elements which express the gene product having the desired activity; wherein at least one step is under microfluidic control. The invention enables the in vitro evolution of nucleic acids and proteins by repeated mutagenesis and iterative applications of the method of the invention.