The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 05, 2020

Filed:

Sep. 09, 2017
Applicant:

Pgfx Patent Holdings, Llc, West Monroe, LA (US);

Inventors:

Gary H. Nelson, Fort Myers, FL (US);

Ryan N Brandt, Fort Myers, FL (US);

Clark Galen, Sarasota, FL (US);

John Kiwczak, Sarasota, FL (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/19 (2015.01); A61L 27/36 (2006.01); A61L 27/54 (2006.01); A61K 45/06 (2006.01); A61K 38/18 (2006.01); C12N 1/06 (2006.01); A61K 35/16 (2015.01); C07K 14/475 (2006.01); A61K 47/42 (2017.01);
U.S. Cl.
CPC ...
A61K 35/19 (2013.01); A61K 35/16 (2013.01); A61K 38/18 (2013.01); A61K 38/1808 (2013.01); A61K 38/1816 (2013.01); A61K 38/1825 (2013.01); A61K 38/1841 (2013.01); A61K 38/1858 (2013.01); A61K 45/06 (2013.01); A61K 47/42 (2013.01); A61L 27/3616 (2013.01); A61L 27/54 (2013.01); C07K 14/475 (2013.01); C12N 1/066 (2013.01); A61L 2300/252 (2013.01); A61L 2300/256 (2013.01); A61L 2300/64 (2013.01); A61L 2430/00 (2013.01);
Abstract

In vitro and in vivo application of sub-atmospheric, negative pressure on growth factor starting material, such as whole blood, extracts growth factors from the platelet granules of the growth factor starting material in a non-destructive medium without activating the clotting process. The extracted growth factors are released into a growth factor composition containing blood plasma, extracellular fluid or interstitial fluid depending upon the type and location of the growth factor starting material. The growth factors have a weight of about 70-76 kDaltons and are applied in either a filtered or unfiltered state topically to the area of a surface wound to effect healing. The extracted growth factors are also injected into soft tissue, such as a torn tendon, to promote tissue growth and healing. The growth factors are released in one method from a patient's own blood. In another method the growth factors are released from a whole blood source and freeze dried by lyophilization. Then at a later date, the freeze-dried product is reconstituted by normal saline for treatment of a patient's wound, for use in a surgical procedure, or for tissue regeneration.


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