The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 05, 2020

Filed:

Mar. 29, 2017
Applicants:

Georgia State University Research Foundation, Inc., Atlanta, GA (US);

University of Georgia Research Foundation, Inc., Athens, GA (US);

Board of Trustees of Michigan State University, East Lansing, MI (US);

Inventors:

Jenny Jie Yang, Marietta, GA (US);

Jian Hu, Atlanta, GA (US);

Edward Brown, Atlanta, GA (US);

Kelley Moremen, Athens, GA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/435 (2006.01); A61K 31/437 (2006.01); G01N 33/68 (2006.01); G01N 33/50 (2006.01); C07K 16/18 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
A61K 31/437 (2013.01); C07K 14/705 (2013.01); C07K 16/18 (2013.01); G01N 33/50 (2013.01); G01N 33/6872 (2013.01); G01N 2500/02 (2013.01);
Abstract

Described herein are compounds that can bind CaSR and/or a CaSR extracellular domain and formulations thereof. Also described herein are methods of inhibiting CaSR and/or treating a disease or disorder associated with a mutation in CaSR by administering a compound or formulation thereof described herein. Also described herein are assays that can be used to identify compounds that can bind an extracellular domain of CaSR.


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