The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 2020

Filed:

Mar. 06, 2014
Applicant:

Macquarie University, North Ryde, NSW, AU;

Inventors:

Lars Matthias Ittner, Chatswood, AU;

Janet Van Eersel, Glebe, AU;

Assignee:

MACQUARIE UNIVERSITY, North Ryde, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); C12Q 1/6883 (2018.01);
U.S. Cl.
CPC ...
G01N 33/6896 (2013.01); C12Q 1/6883 (2013.01); C12Q 2600/136 (2013.01); G01N 2333/4709 (2013.01); G01N 2500/02 (2013.01);
Abstract

The invention relates to methods and assays for identifying compounds as candidates in the development of a drug for the treatment of various diseases including those associated with pathological Tau. The invention also relates to methods and assays for identifying compounds for the treatment of various diseases including those associated with pathological Tau. The invention also relates to cell lines and constructs for use in an assay of the invention. The methods and assays identify a compound as useful in the treatment of a tauopathy if said compound modulates Sil1 expression or activity.


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