The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 2020
Filed:
Oct. 25, 2016
Applicant:
Dow Agrosciences Llc, Indianapolis, IN (US);
Inventors:
Pohao Wang, Carmel, IN (US);
Shreedharan Sriram, Indianapolis, IN (US);
Lakshmi Sastry-Dent, Avon, IN (US);
Assignee:
Dow AgroSciences LLC, Indianapolis, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6876 (2018.01); G16B 25/00 (2019.01); C12Q 1/6895 (2018.01); C12N 15/82 (2006.01); G16B 20/00 (2019.01);
U.S. Cl.
CPC ...
C12Q 1/6876 (2013.01); C12N 15/82 (2013.01); C12Q 1/6895 (2013.01); G16B 20/00 (2019.02); G16B 25/00 (2019.02); C12Q 2600/154 (2013.01); C12Q 2600/158 (2013.01);
Abstract
The present invention is based on the use of the H3K9me2 methylation levels in plant genomes to predict transgene silencing, transgene stability, and/or transgene expression level. Provided are methods and/or systems for generating whole-genome H3K9me2 maps and its use with an assigned threshold value for predicting gene silencing. The methods and/or systems provided herein can be used in high-throughput setting for screening large number of transformed event in a relatively short period of time as compared to existing technologies.