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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10633681 B1

PDFFull Text
Date of Patent:
Apr. 28, 2020

Filed:

Jan. 26, 2018

Apparatus and methods for biosynthetic production of cannabinoids

Applicant:

Teewinot Technologies Limited, Dublin, IE;

Inventors:

Robert Winnicki, Cambridge, MA (US);

Marc Donsky, Denver, CO (US);

Mingyang Sun, Dublin, IE;

Richard Peet, Washington, DC (US);

Assignee:

Teewinot Technologies Limited, Dublin, IE;

Attorney:

Schwegman Lundberg & Woessner, P.A.

Primary Examiner:

Nathan A Bowers

Int. Cl.
CPC ...
C12M 1/00 (2006.01); C12M 3/00 (2006.01); C12P 17/06 (2006.01); C12M 1/34 (2006.01); C12M 1/40 (2006.01); C12P 7/22 (2006.01); C12P 7/42 (2006.01); C12N 9/02 (2006.01); C12M 1/36 (2006.01); C07C 29/80 (2006.01); C07C 37/01 (2006.01); C07C 37/74 (2006.01);
U.S. Cl.
CPC ...
C12P 17/06 (2013.01); C07C 29/80 (2013.01); C07C 37/01 (2013.01); C07C 37/74 (2013.01); C12M 21/18 (2013.01); C12M 29/00 (2013.01); C12M 29/04 (2013.01); C12M 41/12 (2013.01); C12M 41/26 (2013.01); C12M 41/30 (2013.01); C12M 41/32 (2013.01); C12M 41/40 (2013.01); C12M 41/48 (2013.01); C12M 47/10 (2013.01); C12N 9/0004 (2013.01); C12P 7/22 (2013.01); C12P 7/42 (2013.01); C12Y 121/03 (2013.01); C12Y 121/03007 (2015.07); C12Y 121/03008 (2015.07);
Abstract

The present invention provides an apparatus and methods for producing tetrahydrocannabinolic acid (THCA), cannabichromenic acid (CBCA) and cannabichromenic acid (CBCA) in different ratios. The apparatus comprises: (i) a bioreactor comprising (a) an automated supply system configured to deliver a first automated supply of cannabigerolic acid (CBGA), a cannabinoid acid synthase, and a reaction mixture; and (b) a second automated system to cease the reaction; (ii) a controller configured to modify a property of the reaction mixture to produce the desired products; and (iii) an extractor configured to recover the tetrahydrocannabinolic acid (THCA), cannabichromenic acid (CBCA) or cannabidiolic acid (CBDA) and cannabichromenic acid.

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