The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 2020

Filed:

Mar. 24, 2016
Applicant:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Inventors:

Andreas Gallusser, Penzberg, DE;

Dieter Heindl, Paehl, DE;

Michael Schraeml, Penzberg, DE;

Christoph Seidel, Weilheim, DE;

Herbert von der Eltz, Weilheim, DE;

Assignee:

Roche Diagnostic Operations, Inc., Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 19/00 (2006.01); C07K 16/32 (2006.01); C07K 16/18 (2006.01);
U.S. Cl.
CPC ...
C07K 19/00 (2013.01); C07K 16/18 (2013.01); C07K 16/2863 (2013.01); C07K 16/32 (2013.01); C07K 2317/31 (2013.01); C07K 2317/34 (2013.01); C07K 2317/55 (2013.01); C07K 2317/626 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract

A binding agent of the Formula A-a':a-S-b:b′-B:X(n), wherein A as well as B is a monovalent binder, a′:a as well as b:b′ is a binding pair wherein a′ and a do not interfere with the binding of b to b′ and vice versa, S is a spacer of at least 1 nm in length, :X denotes a functional moiety bound either covalently or via a binding pair to at least one of a′, a, b, b′ or S, (n) is an integer and at least 1, — represents a covalent bond, and the linker a-S-b has a length of 6 to 100 nm. Also disclosed are methods of producing such binding agent and certain uses thereof.


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