The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 2020
Filed:
Sep. 15, 2016
Applicant:
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
Laurence J. N. Cooper, Houston, TX (US);
Bipulendu Jena, Houston, TX (US);
Assignee:
BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 16/28 (2006.01); C12N 5/0783 (2010.01); C07K 14/725 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2809 (2013.01); A61K 39/39558 (2013.01); C07K 14/7051 (2013.01); C07K 16/2833 (2013.01); C07K 16/2896 (2013.01); C12N 5/0636 (2013.01); C07K 2317/34 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01);
Abstract
Antibodies and antigen binding fragments thereof are provided that bind to T-cell receptors (e.g., TCRα), essentially independent of T-cell epitope specificity. Methods for manipulation of T-cells and methods of treatment using such antibodies are likewise provided.