The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 2020
Filed:
Aug. 30, 2017
Jiangsu Hengrui Medicine Co., Ltd., Lianyungang, Jiangsu, CN;
Shanghai Hengrui Pharmaceutical Co., Ltd., Shanghai, CN;
Fanglong Yang, Shanghai, CN;
Weimin Wang, Shanghai, CN;
Xiaodong Li, Shanghai, CN;
Gang Chen, Shanghai, CN;
Feng He, Shanghai, CN;
Weikang Tao, Shanghai, CN;
Jinagsu Hengrui Medicine Co., Ltd, Lianyungang, Jiangsu, CN;
Shanghai Hengrui Pharmaceutical Co., Ltd., Shanghai, CN;
Abstract
The present invention relates to an oxopicolinamide derivative, a preparation method therefor and the pharmaceutical use thereof. In particular, the present invention relates to an oxopicolinamide derivative as shown in the general formula (AI), a preparation method therefor and a pharmaceutical composition comprising the derivative, and to the use thereof as a therapeutic agent, in particular as an inhibitor of blood coagulation factor XIa (Factor XIa, FXIa for short) and the use thereof in the preparation of a drug for treating diseases such as thromboembolism, wherein the definition of each substituent in the general formula (AI) is the same as defined in the description.